2022 Lexus LS 500 vs Audi S6 — Side by Side Comparison

How does the 2022 Lexus LS 500 compare to the Audi S6? We put them side by side using EPA fuel economy data and NHTSA safety ratings.

Specifications Comparison

FeatureLexus LS 500Audi S6
Combined MPG2222
City MPG1818
Highway MPG2928
Body StyleSedanSedan
DriveRWD4WD
Fuel TypePremiumPremium
Safety RatingN/A / 5N/A / 5
Recalls00
Trims Available21

Fuel Economy

The Audi S6 is more fuel efficient by 0 MPG combined. Over a year, the Audi S6 saves approximately $0 in fuel costs.

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