2022 Lexus IS 300 vs Acura Tlx — Side by Side Comparison

How does the 2022 Lexus IS 300 compare to the Acura Tlx? We put them side by side using EPA fuel economy data and NHTSA safety ratings.

Specifications Comparison

FeatureLexus IS 300Acura Tlx
Combined MPG2525
City MPG2122
Highway MPG3131
Body StyleCompact SedanCompact Sedan
DriveRWDFWD
Fuel TypePremiumPremium
Safety RatingN/A / 5N/A / 5
Recalls00
Trims Available22

Fuel Economy

The Acura Tlx is more fuel efficient by 0 MPG combined. Over a year, the Acura Tlx saves approximately $0 in fuel costs.

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