2006 Toyota Sienna

Van Regular
Toyota Sienna 2006
19MPG Combined
2 Trims
Updated February 27, 2026

Looking at the 2006 Toyota Sienna? This Van offers 17–19 combined MPG depending on trim and comes with 2 available configurations. We break down the specs, safety data, and how it compares to the competition.

2006 Toyota Sienna Specifications

SpecValue
Combined MPG17–19 combined MPG depending on trim
City MPG17
Highway MPG24
Body StyleVan
Fuel TypeRegular
DriveFWD
Available Trims2

Available Trims

TrimMPG (City/Hwy/Combined)EngineTransmission
Auto17/24/193.3L 6cylAutomatic 5-spd
Auto15/21/173.3L 6cylAutomatic 5-spd

Annual Fuel Cost

Based on EPA estimates, the 2006 Toyota Sienna costs approximately $2,450 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

Compare the 2006 Toyota Sienna

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