2021 Toyota Sienna Hybrid
36MPG
Combined
2
Trims
2021
Updated February 27, 2026
The 2021 Toyota Sienna Hybrid Van provides 35–36 combined MPG depending on trim. We’ve compiled EPA fuel economy data, NHTSA safety ratings, and recall history so you can make an informed decision.
2021 Toyota Sienna Hybrid Specifications
| Spec | Value |
|---|---|
| Combined MPG | 35–36 combined MPG depending on trim |
| City MPG | 36 |
| Highway MPG | 36 |
| Body Style | Van |
| Fuel Type | Regular |
| Drive | FWD |
| Available Trims | 2 |
Available Trims
| Trim | MPG (City/Hwy/Combined) | Engine | Transmission |
|---|---|---|---|
| 4 cyl | 36/36/36 | 2.5L 4cyl | Automatic (AV-S6) |
| 4 cyl | 35/36/35 | 2.5L 4cyl | Automatic (AV-S6) |
Annual Fuel Cost
Based on EPA estimates, the 2021 Toyota Sienna Hybrid costs approximately $1,225 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.
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