2022 Mercedes-Benz S580 4matic Maybach

Full-Size Sedan Premium
Mercedes-Benz S580 4matic Maybach 2022
18MPG Combined
1 Trim
← 2021 2022 2023 →
Updated February 27, 2026

Looking at the 2022 Mercedes-Benz S580 4matic Maybach? This Full-Size Sedan offers 18 combined MPG and comes with 1 available configurations. We break down the specs, safety data, and how it compares to the competition.

2022 Mercedes-Benz S580 4matic Maybach Specifications

SpecValue
Combined MPG18 combined MPG
City MPG15
Highway MPG24
Body StyleFull-Size Sedan
Fuel TypePremium
DriveAWD
Available Trims1

Annual Fuel Cost

Based on EPA estimates, the 2022 Mercedes-Benz S580 4matic Maybach costs approximately $3,250 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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