2021 Mercedes-Benz S580 4matic Maybach

Full-Size Sedan Premium
Mercedes-Benz S580 4matic Maybach 2021
19MPG Combined
1 Trim
2021 2022 →
Updated February 27, 2026

Get the full picture on the 2021 Mercedes-Benz S580 4matic Maybach. As a Full-Size Sedan, it achieves 19 combined MPG and has not yet been rated by NHTSA. Below you’ll find detailed specs for every trim, plus recall information and competitor comparisons.

2021 Mercedes-Benz S580 4matic Maybach Specifications

SpecValue
Combined MPG19 combined MPG
City MPG16
Highway MPG24
Body StyleFull-Size Sedan
Fuel TypePremium
Drive4WD
Available Trims1

Annual Fuel Cost

Based on EPA estimates, the 2021 Mercedes-Benz S580 4matic Maybach costs approximately $3,050 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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