2010 Mercedes-Benz S550 4matic

Full-Size Sedan Premium
Mercedes-Benz S550 4matic 2010
17MPG Combined
1 Trim
← 2009 2010 2011 →
Updated February 27, 2026

The 2010 Mercedes-Benz S550 4matic Full-Size Sedan provides 17 combined MPG. We’ve compiled EPA fuel economy data, NHTSA safety ratings, and recall history so you can make an informed decision.

2010 Mercedes-Benz S550 4matic Specifications

SpecValue
Combined MPG17 combined MPG
City MPG14
Highway MPG21
Body StyleFull-Size Sedan
Fuel TypePremium
Drive4WD
Available Trims1

Annual Fuel Cost

Based on EPA estimates, the 2010 Mercedes-Benz S550 4matic costs approximately $3,450 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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