2000 Mercedes-Benz S500

Full-Size Sedan Premium
Mercedes-Benz S500 2000
17MPG Combined
1 Trim
2000 2001 →
Updated February 27, 2026

Get the full picture on the 2000 Mercedes-Benz S500. As a Full-Size Sedan, it achieves 17 combined MPG and has not yet been rated by NHTSA. Below you’ll find detailed specs for every trim, plus recall information and competitor comparisons.

2000 Mercedes-Benz S500 Specifications

SpecValue
Combined MPG17 combined MPG
City MPG15
Highway MPG21
Body StyleFull-Size Sedan
Fuel TypePremium
DriveRWD
Available Trims1

Annual Fuel Cost

Based on EPA estimates, the 2000 Mercedes-Benz S500 costs approximately $3,450 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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