2006 Mercedes-Benz E500
18MPG
Combined
1
Trim
← 2005
2006
Updated February 27, 2026
Looking at the 2006 Mercedes-Benz E500? This Sedan offers 18 combined MPG and comes with 1 available configurations. We break down the specs, safety data, and how it compares to the competition.
2006 Mercedes-Benz E500 Specifications
| Spec | Value |
|---|---|
| Combined MPG | 18 combined MPG |
| City MPG | 15 |
| Highway MPG | 23 |
| Body Style | Sedan |
| Fuel Type | Premium |
| Drive | RWD |
| Available Trims | 1 |
Annual Fuel Cost
Based on EPA estimates, the 2006 Mercedes-Benz E500 costs approximately $3,250 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.
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