2021 Mercedes-Benz E450 4matic Convertible

Compact Sedan Premium
Mercedes-Benz E450 4matic Convertible 2021
25MPG Combined
1 Trim
← 2020 2021 2022 →
Updated February 27, 2026

The 2021 Mercedes-Benz E450 4matic Convertible Compact Sedan provides 25 combined MPG. We’ve compiled EPA fuel economy data, NHTSA safety ratings, and recall history so you can make an informed decision.

2021 Mercedes-Benz E450 4matic Convertible Specifications

SpecValue
Combined MPG25 combined MPG
City MPG23
Highway MPG29
Body StyleCompact Sedan
Fuel TypePremium
Drive4WD
Available Trims1

Annual Fuel Cost

Based on EPA estimates, the 2021 Mercedes-Benz E450 4matic Convertible costs approximately $2,350 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

Compare the 2021 Mercedes-Benz E450 4matic Convertible

See how it stacks up against similar vehicles:

Other Model Years

Check Vehicle History

Considering a used Mercedes-Benz E450 4matic Convertible? Get a comprehensive vehicle history report including accident records, ownership history, and more.

🔍 Check Mercedes-Benz E450 4matic Convertible Vehicle History Check VIN →
Check Vehicle History

Get the full story — accidents, ownership, recalls, odometer, and more. Decode any VIN instantly.

Check VIN
Buying a used Mercedes-Benz E450 4matic Convertible? Check VIN on RedVIN