2012 Mercedes-Benz E350 Coupe

Compact Sedan Premium
Mercedes-Benz E350 Coupe 2012
23MPG Combined
2 Trims
← 2011 2012 2013 →
Updated February 27, 2026

The 2012 Mercedes-Benz E350 Coupe Compact Sedan provides 22–23 combined MPG depending on trim. We’ve compiled EPA fuel economy data, NHTSA safety ratings, and recall history so you can make an informed decision.

2012 Mercedes-Benz E350 Coupe Specifications

SpecValue
Combined MPG22–23 combined MPG depending on trim
City MPG20
Highway MPG28
Body StyleCompact Sedan
Fuel TypePremium
DriveRWD
Available Trims2

Available Trims

TrimMPG (City/Hwy/Combined)EngineTransmission
Auto19/28/223.5L 6cylAutomatic 7-spd
Auto20/28/233.5L 6cylAutomatic 7-spd

Annual Fuel Cost

Based on EPA estimates, the 2012 Mercedes-Benz E350 Coupe costs approximately $2,600 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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