2012 Mercedes-Benz E350 4matic (Wagon)

Wagon Premium
Mercedes-Benz E350 4matic (Wagon) 2012
22MPG Combined
1 Trim
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Updated February 27, 2026

The 2012 Mercedes-Benz E350 4matic (Wagon) is a Wagon that delivers 22 combined MPG. Here’s everything you need to know about this vehicle, from fuel economy to safety ratings.

2012 Mercedes-Benz E350 4matic (Wagon) Specifications

SpecValue
Combined MPG22 combined MPG
City MPG19
Highway MPG27
Body StyleWagon
Fuel TypePremium
Drive4WD
Available Trims1

Annual Fuel Cost

Based on EPA estimates, the 2012 Mercedes-Benz E350 4matic (Wagon) costs approximately $2,650 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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