2001 Mercedes-Benz E320 4Matic

Sedan Premium
Mercedes-Benz E320 4Matic 2001
20MPG Combined
1 Trim
← 2000 2001 2002 →
Updated February 27, 2026

The 2001 Mercedes-Benz E320 4Matic Sedan provides 20 combined MPG. We’ve compiled EPA fuel economy data, NHTSA safety ratings, and recall history so you can make an informed decision.

2001 Mercedes-Benz E320 4Matic Specifications

SpecValue
Combined MPG20 combined MPG
City MPG18
Highway MPG24
Body StyleSedan
Fuel TypePremium
DriveAWD/4WD
Available Trims1

Annual Fuel Cost

Based on EPA estimates, the 2001 Mercedes-Benz E320 4Matic costs approximately $2,900 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

Compare the 2001 Mercedes-Benz E320 4Matic

See how it stacks up against similar vehicles:

Other Model Years

Check Vehicle History

Considering a used Mercedes-Benz E320 4Matic? Get a comprehensive vehicle history report including accident records, ownership history, and more.

🔍 Check Mercedes-Benz E320 4Matic Vehicle History Check VIN →
Check Vehicle History

Get the full story — accidents, ownership, recalls, odometer, and more. Decode any VIN instantly.

Check VIN
Buying a used Mercedes-Benz E320 4Matic? Check VIN on RedVIN