2006 Mercedes-Benz C350

Compact Sedan Premium
Mercedes-Benz C350 2006
21MPG Combined
2 Trims
2006 2007 →
Updated February 27, 2026

Looking at the 2006 Mercedes-Benz C350? This Compact Sedan offers 21 combined MPG and comes with 2 available configurations. We break down the specs, safety data, and how it compares to the competition.

2006 Mercedes-Benz C350 Specifications

SpecValue
Combined MPG21 combined MPG
City MPG18
Highway MPG27
Body StyleCompact Sedan
Fuel TypePremium
DriveRWD
Available Trims2

Available Trims

TrimMPG (City/Hwy/Combined)EngineTransmission
Auto18/27/213.5L 6cylAutomatic 7-spd
Man18/26/213.5L 6cylManual 6-spd

Annual Fuel Cost

Based on EPA estimates, the 2006 Mercedes-Benz C350 costs approximately $2,800 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

Compare the 2006 Mercedes-Benz C350

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