2021 Mercedes-Benz C300 4matic

Compact Sedan Premium
Mercedes-Benz C300 4matic 2021
27MPG Combined
1 Trim
← 2020 2021 2022 →
Updated February 27, 2026

The 2021 Mercedes-Benz C300 4matic Compact Sedan provides 27 combined MPG. We’ve compiled EPA fuel economy data, NHTSA safety ratings, and recall history so you can make an informed decision.

2021 Mercedes-Benz C300 4matic Specifications

SpecValue
Combined MPG27 combined MPG
City MPG23
Highway MPG33
Body StyleCompact Sedan
Fuel TypePremium
Drive4WD
Available Trims1

Annual Fuel Cost

Based on EPA estimates, the 2021 Mercedes-Benz C300 4matic costs approximately $2,150 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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