2021 Lexus RX 450h

30MPG
Combined
1
Trim
Updated February 27, 2026
Get the full picture on the 2021 Lexus RX 450h. As a SUV, it achieves 30 combined MPG and has not yet been rated by NHTSA. Below you’ll find detailed specs for every trim, plus recall information and competitor comparisons.
2021 Lexus RX 450h Specifications
| Spec | Value |
|---|---|
| Combined MPG | 30 combined MPG |
| City MPG | 31 |
| Highway MPG | 28 |
| Body Style | SUV |
| Fuel Type | Premium |
| Drive | AWD |
| Available Trims | 1 |
Annual Fuel Cost
Based on EPA estimates, the 2021 Lexus RX 450h costs approximately $1,950 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.
Compare the 2021 Lexus RX 450h
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Other Model Years
- 2022 Lexus RX 450h
- 2021 (this page)
- 2020 Lexus RX 450h
- 2019 Lexus RX 450h
- 2018 Lexus RX 450h
- 2017 Lexus RX 450h
- 2016 Lexus RX 450h
- 2015 Lexus RX 450h
- 2014 Lexus RX 450h
- 2013 Lexus RX 450h
- 2012 Lexus RX 450h
- 2011 Lexus RX 450h
- 2010 Lexus RX 450h
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