2010 Lexus RX 450h

SUV Premium
Lexus RX 450h 2010
30MPG Combined
2 Trims
2010 2011 →
Updated February 27, 2026

The 2010 Lexus RX 450h SUV provides 29–30 combined MPG depending on trim. We’ve compiled EPA fuel economy data, NHTSA safety ratings, and recall history so you can make an informed decision.

2010 Lexus RX 450h Specifications

SpecValue
Combined MPG29–30 combined MPG depending on trim
City MPG32
Highway MPG28
Body StyleSUV
Fuel TypePremium
DriveAWD
Available Trims2

Available Trims

TrimMPG (City/Hwy/Combined)EngineTransmission
6 cyl30/28/293.5L 6cylAutomatic (AV-S6)
6 cyl32/28/303.5L 6cylAutomatic (AV-S6)

Annual Fuel Cost

Based on EPA estimates, the 2010 Lexus RX 450h costs approximately $1,975 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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