2008 Lexus RX 350

SUV Premium
Lexus RX 350 2008
20MPG Combined
4 Trims
Updated February 27, 2026

Looking at the 2008 Lexus RX 350? This SUV offers 19–20 combined MPG depending on trim and comes with 4 available configurations. We break down the specs, safety data, and how it compares to the competition.

2008 Lexus RX 350 Specifications

SpecValue
Combined MPG19–20 combined MPG depending on trim
City MPG18
Highway MPG23
Body StyleSUV
Fuel TypePremium
DriveFWD
Available Trims4

Available Trims

TrimMPG (City/Hwy/Combined)EngineTransmission
Auto18/23/203.5L 6cylAutomatic 5-spd
6 cyl18/23/203.5L 6cylAutomatic (S5)
Auto17/22/193.5L 6cylAutomatic 5-spd
6 cyl17/22/193.5L 6cylAutomatic (S5)

Annual Fuel Cost

Based on EPA estimates, the 2008 Lexus RX 350 costs approximately $2,975 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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