2006 Lexus RX 330

SUV Premium
Lexus RX 330 2006
20MPG Combined
4 Trims
← 2005 2006
Updated February 27, 2026

The 2006 Lexus RX 330 is a SUV that delivers 18–20 combined MPG depending on trim. Here’s everything you need to know about this vehicle, from fuel economy to safety ratings.

2006 Lexus RX 330 Specifications

SpecValue
Combined MPG18–20 combined MPG depending on trim
City MPG17
Highway MPG23
Body StyleSUV
Fuel TypePremium
DriveFWD
Available Trims4

Available Trims

TrimMPG (City/Hwy/Combined)EngineTransmission
Auto17/23/203.3L 6cylAutomatic 5-spd
6 cyl17/23/193.3L 6cylAutomatic (S5)
Auto16/22/193.3L 6cylAutomatic 5-spd
6 cyl16/22/183.3L 6cylAutomatic (S5)

Annual Fuel Cost

Based on EPA estimates, the 2006 Lexus RX 330 costs approximately $3,062 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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