2022 Lexus LS 500h

25MPG
Combined
1
Trim
Updated February 27, 2026
The 2022 Lexus LS 500h is a Sedan that delivers 25 combined MPG. Here’s everything you need to know about this vehicle, from fuel economy to safety ratings.
2022 Lexus LS 500h Specifications
| Spec | Value |
|---|---|
| Combined MPG | 25 combined MPG |
| City MPG | 22 |
| Highway MPG | 29 |
| Body Style | Sedan |
| Fuel Type | Premium |
| Drive | AWD |
| Available Trims | 1 |
Annual Fuel Cost
Based on EPA estimates, the 2022 Lexus LS 500h costs approximately $2,350 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.
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Other Model Years
- 2025 Lexus LS 500h
- 2024 Lexus LS 500h
- 2023 Lexus LS 500h
- 2022 (this page)
- 2021 Lexus LS 500h
- 2020 Lexus LS 500h
- 2019 Lexus LS 500h
- 2018 Lexus LS 500h
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