2010 Lexus IS 350/Is 350C
20MPG
Combined
1
Trim
2010
2011 →
Updated February 27, 2026
The 2010 Lexus IS 350/Is 350C is a Compact Sedan that delivers 20 combined MPG. Here’s everything you need to know about this vehicle, from fuel economy to safety ratings.
2010 Lexus IS 350/Is 350C Specifications
| Spec | Value |
|---|---|
| Combined MPG | 20 combined MPG |
| City MPG | 18 |
| Highway MPG | 25 |
| Body Style | Compact Sedan |
| Fuel Type | Premium |
| Drive | RWD |
| Available Trims | 1 |
Annual Fuel Cost
Based on EPA estimates, the 2010 Lexus IS 350/Is 350C costs approximately $2,900 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.
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