2012 Lexus IS 250/Is 250C

Compact Sedan Premium
Lexus IS 250/Is 250C 2012
24MPG Combined
2 Trims
Updated February 27, 2026

The 2012 Lexus IS 250/Is 250C Compact Sedan provides 22–24 combined MPG depending on trim. We’ve compiled EPA fuel economy data, NHTSA safety ratings, and recall history so you can make an informed decision.

2012 Lexus IS 250/Is 250C Specifications

SpecValue
Combined MPG22–24 combined MPG depending on trim
City MPG21
Highway MPG29
Body StyleCompact Sedan
Fuel TypePremium
DriveRWD
Available Trims2

Available Trims

TrimMPG (City/Hwy/Combined)EngineTransmission
Man19/27/222.5L 6cylManual 6-spd
6 cyl21/29/242.5L 6cylAutomatic (S6)

Annual Fuel Cost

Based on EPA estimates, the 2012 Lexus IS 250/Is 250C costs approximately $2,550 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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