2010 Lexus IS 250/Is 250C
24MPG
Combined
2
Trims
2010
2011 →
Updated February 27, 2026
Looking at the 2010 Lexus IS 250/Is 250C? This Compact Sedan offers 21–24 combined MPG depending on trim and comes with 2 available configurations. We break down the specs, safety data, and how it compares to the competition.
2010 Lexus IS 250/Is 250C Specifications
| Spec | Value |
|---|---|
| Combined MPG | 21–24 combined MPG depending on trim |
| City MPG | 21 |
| Highway MPG | 29 |
| Body Style | Compact Sedan |
| Fuel Type | Premium |
| Drive | RWD |
| Available Trims | 2 |
Available Trims
| Trim | MPG (City/Hwy/Combined) | Engine | Transmission |
|---|---|---|---|
| Man | 18/26/21 | 2.5L 6cyl | Manual 6-spd |
| 6 cyl | 21/29/24 | 2.5L 6cyl | Automatic (S6) |
Annual Fuel Cost
Based on EPA estimates, the 2010 Lexus IS 250/Is 250C costs approximately $2,625 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.
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