2006 Lexus IS 250
24MPG
Combined
3
Trims
2006
2007 →
Updated February 27, 2026
Get the full picture on the 2006 Lexus IS 250. As a Compact Sedan, it achieves 21–24 combined MPG depending on trim and has not yet been rated by NHTSA. Below you’ll find detailed specs for every trim, plus recall information and competitor comparisons.
2006 Lexus IS 250 Specifications
| Spec | Value |
|---|---|
| Combined MPG | 21–24 combined MPG depending on trim |
| City MPG | 21 |
| Highway MPG | 29 |
| Body Style | Compact Sedan |
| Fuel Type | Premium |
| Drive | RWD |
| Available Trims | 3 |
Available Trims
| Trim | MPG (City/Hwy/Combined) | Engine | Transmission |
|---|---|---|---|
| Man | 18/26/21 | 2.5L 6cyl | Manual 6-spd |
| 6 cyl | 21/29/24 | 2.5L 6cyl | Automatic (S6) |
| 6 cyl | 20/26/22 | 2.5L 6cyl | Automatic (S6) |
Annual Fuel Cost
Based on EPA estimates, the 2006 Lexus IS 250 costs approximately $2,633 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.
Compare the 2006 Lexus IS 250
See how it stacks up against similar vehicles:
Other Model Years
- 2015 Lexus IS 250
- 2014 Lexus IS 250
- 2013 Lexus IS 250
- 2012 Lexus IS 250
- 2011 Lexus IS 250
- 2010 Lexus IS 250
- 2009 Lexus IS 250
- 2008 Lexus IS 250
- 2007 Lexus IS 250
- 2006 (this page)
Check Vehicle History
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