2006 Honda Odyssey

Van Regular
Honda Odyssey 2006
20MPG Combined
2 Trims
Updated February 27, 2026

The 2006 Honda Odyssey Van provides 19–20 combined MPG depending on trim. We’ve compiled EPA fuel economy data, NHTSA safety ratings, and recall history so you can make an informed decision.

2006 Honda Odyssey Specifications

SpecValue
Combined MPG19–20 combined MPG depending on trim
City MPG17
Highway MPG26
Body StyleVan
Fuel TypeRegular
DriveFWD
Available Trims2

Available Trims

TrimMPG (City/Hwy/Combined)EngineTransmission
Auto17/23/193.5L 6cylAutomatic 5-spd
Auto17/26/203.5L 6cylAutomatic 5-spd

Annual Fuel Cost

Based on EPA estimates, the 2006 Honda Odyssey costs approximately $2,250 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.

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