2021 Ford F150 Pickup 2WD
21MPG
Combined
3
Trims
Updated February 27, 2026
Looking at the 2021 Ford F150 Pickup 2WD? This Truck offers 19–21 combined MPG depending on trim and comes with 3 available configurations. We break down the specs, safety data, and how it compares to the competition.
2021 Ford F150 Pickup 2WD Specifications
| Spec | Value |
|---|---|
| Combined MPG | 19–21 combined MPG depending on trim |
| City MPG | 20 |
| Highway MPG | 24 |
| Body Style | Truck |
| Fuel Type | Flex Fuel |
| Drive | RWD |
| Available Trims | 3 |
Available Trims
| Trim | MPG (City/Hwy/Combined) | Engine | Transmission |
|---|---|---|---|
| 6 cyl | 20/24/21 | 3.3L 6cyl | Automatic (S10) |
| 8 cyl | 17/24/20 | 5.0L 8cyl | Automatic (S10) |
| 8 cyl | 17/24/19 | 5.0L 8cyl | Automatic (S10) |
Annual Fuel Cost
Based on EPA estimates, the 2021 Ford F150 Pickup 2WD costs approximately $2,200 per year in fuel. This assumes 15,000 miles driven annually and current fuel prices.
Compare the 2021 Ford F150 Pickup 2WD
See how it stacks up against similar vehicles:
Other Model Years
- 2023 Ford F150 Pickup 2WD
- 2022 Ford F150 Pickup 2WD
- 2021 (this page)
- 2020 Ford F150 Pickup 2WD
- 2019 Ford F150 Pickup 2WD
- 2018 Ford F150 Pickup 2WD
- 2017 Ford F150 Pickup 2WD
- 2016 Ford F150 Pickup 2WD
- 2015 Ford F150 Pickup 2WD
- 2014 Ford F150 Pickup 2WD
- 2013 Ford F150 Pickup 2WD
- 2012 Ford F150 Pickup 2WD
- 2011 Ford F150 Pickup 2WD
- 2010 Ford F150 Pickup 2WD
- 2009 Ford F150 Pickup 2WD
- 2008 Ford F150 Pickup 2WD
- 2007 Ford F150 Pickup 2WD
- 2006 Ford F150 Pickup 2WD
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